Prioritizing individual genetic variants after kernel machine testing using variable selection
نویسندگان
چکیده
منابع مشابه
Prioritizing individual genetic variants after kernel machine testing using variable selection.
Kernel machine learning methods, such as the SNP-set kernel association test (SKAT), have been widely used to test associations between traits and genetic polymorphisms. In contrast to traditional single-SNP analysis methods, these methods are designed to examine the joint effect of a set of related SNPs (such as a group of SNPs within a gene or a pathway) and are able to identify sets of SNPs ...
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ژورنال
عنوان ژورنال: Genetic Epidemiology
سال: 2016
ISSN: 0741-0395
DOI: 10.1002/gepi.21993